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Targeted large fragment deletion in plants using paired crRNAs with type I CRISPR system

The CRISPR‐Cas systems have been widely used as genome editing tools, with type II and V systems typically introducing small indels, and type I system mediating long‐range deletions. However, the precision of type I systems for large fragment deletion is still remained to be optimized. Here, we deve...

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Detalles Bibliográficos
Autores principales: Li, Yingnan, Huang, Boyu, Chen, Jian, Huang, Liangliang, Xu, Jianghai, Wang, Yingying, Cui, Guanghui, Zhao, Haiming, Xin, Beibei, Song, Weibin, Zhu, Jian‐Kang, Lai, Jinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579709/
https://www.ncbi.nlm.nih.gov/pubmed/37641539
http://dx.doi.org/10.1111/pbi.14122