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CTNNAL1 deficiency suppresses CFTR expression in HDM-induced asthma mouse model through ROCK1-CAL signaling pathway: CTNNAL1 increases CFTR expression in asthma mouse model

The downregulation of adhesion molecule catenin alpha-like 1 (CTNNAL1) in airway epithelial cells of asthma patients and house dust mite (HDM)-induced asthma animal models was illustrated in our previous study. It is assumed to contribute to airway inflammation and mucus hypersecretion. In this work...

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Detalles Bibliográficos
Autores principales: Wu, Di, Zhu, Jiahui, Yang, Fang, Li, Riwang, Liu, Lexin, Liu, Dahai, Liu, Chi, Qu, Xiangping, Liu, Huijun, Ji, Ming, Qin, Xiaoqun, Hua, Lan, Xiang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579809/
https://www.ncbi.nlm.nih.gov/pubmed/37715489
http://dx.doi.org/10.3724/abbs.2023152