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The effect of Toll-like receptor agonists on the immunogenicity of MVA-SARS-2-S vaccine after intranasal administration in mice

BACKGROUND AND AIMS: Modified Vaccinia virus Ankara (MVA) represents a promising vaccine vector for respiratory administration to induce protective lung immunity including tertiary lymphoid structure, the bronchus-associated lymphoid tissue (BALT). However, MVA expressing the severe acute respirator...

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Detalles Bibliográficos
Autores principales: Do, Kim Thi Hoang, Willenzon, Stefanie, Ristenpart, Jasmin, Janssen, Anika, Volz, Asisa, Sutter, Gerd, Förster, Reinhold, Bošnjak, Berislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580083/
https://www.ncbi.nlm.nih.gov/pubmed/37854858
http://dx.doi.org/10.3389/fcimb.2023.1259822