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IL-10 Modulation Increases Pyrazinamide’s Antimycobacterial Efficacy against Mycobacterium tuberculosis Infection in Mice

Mechanisms to shorten the duration of tuberculosis (TB) treatment include new drug formulations or schedules and the development of host-directed therapies (HDTs) that better enable the host immune system to eliminate Mycobacterium tuberculosis. Previous studies have shown that pyrazinamide, a first...

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Detalles Bibliográficos
Autores principales: Dwivedi, Varun, Gautam, Shalini, Beamer, Gillian, Stromberg, Paul C., Headley, Colwyn A., Turner, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580111/
https://www.ncbi.nlm.nih.gov/pubmed/37279084
http://dx.doi.org/10.4049/immunohorizons.2200077