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Pregnane X receptor (PXR) deficiency protects against spinal cord injury by activating NRF2/HO‐1 pathway
INTRODUCTION: As a devastating neurological disease, spinal cord injury (SCI) results in severe tissue loss and neurological dysfunction. Pregnane X receptor (PXR) is a ligand‐activated nuclear receptor with a major regulatory role in xenobiotic and endobiotic metabolism and recently has been implic...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580351/ https://www.ncbi.nlm.nih.gov/pubmed/37269088 http://dx.doi.org/10.1111/cns.14279 |