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Pregnane X receptor (PXR) deficiency protects against spinal cord injury by activating NRF2/HO‐1 pathway

INTRODUCTION: As a devastating neurological disease, spinal cord injury (SCI) results in severe tissue loss and neurological dysfunction. Pregnane X receptor (PXR) is a ligand‐activated nuclear receptor with a major regulatory role in xenobiotic and endobiotic metabolism and recently has been implic...

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Detalles Bibliográficos
Autores principales: Xuan, Li‐Na, Hu, Zhen‐Xin, Jiang, Zhen‐Fu, Zhang, Cong, Sun, Xiao‐Wan, Ming, Wen‐Hua, Liu, Hui‐Tao, Qiao, Rong‐Fang, Shen, Lin‐Jie, Liu, Shao‐Bo, Wang, Guan‐Yu, Wen, Lin, Luan, Zhi‐Lin, Yin, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580351/
https://www.ncbi.nlm.nih.gov/pubmed/37269088
http://dx.doi.org/10.1111/cns.14279