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Gm527 deficiency in dentate gyrus improves memory through upregulating dopamine D1 receptor pathway

AIMS: Dopamine D1 receptor (D1R) hypofunction is associated with negative and cognitive symptoms in schizophrenia; therefore, the mechanism of D1R function modulation needs further investigation. Gm527 is the rodent homologous of the schizophrenia‐related gene C14orf28, encoding a predicated D1R‐int...

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Detalles Bibliográficos
Autores principales: Jia, Jie, Peng, Hualing, Tian, Rui, Zhou, Hong, Zheng, Hua, Liu, Bo, Lu, Yisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580352/
https://www.ncbi.nlm.nih.gov/pubmed/37248637
http://dx.doi.org/10.1111/cns.14259