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Increasing brain N‐acetylneuraminic acid alleviates hydrocephalus‐induced neurological deficits

AIMS: This metabolomic study aimed to evaluate the role of N‐acetylneuraminic acid (Neu5Ac) in the neurological deficits of normal pressure hydrocephalus (NPH) and its potential therapeutic effect. METHODS: We analyzed the metabolic profiles of NPH using cerebrospinal fluid with multivariate and uni...

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Detalles Bibliográficos
Autores principales: Wang, Zhangyang, Nie, Xiaoqun, Gao, Fang, Tang, Yanmin, Ma, Yuanyuan, Zhang, Yiying, Gao, Yanqin, Yang, Chen, Ding, Jing, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580356/
https://www.ncbi.nlm.nih.gov/pubmed/37222223
http://dx.doi.org/10.1111/cns.14253