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TL1A promotes the postoperative cognitive dysfunction in mice through NLRP3‐mediated A1 differentiation of astrocytes

AIM: We investigated the mechanism, whereby tumor necrosis factor‐like ligand 1A (TL1A) mediates the A1 differentiation of astrocytes in postoperative cognitive dysfunction (POCD). METHODS: The cognitive and behavioral abilities of mice were assessed by Morris water maze and open field tests, while...

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Detalles Bibliográficos
Autores principales: Wang, Genghuan, Shen, Jian, Zhai, Liping, Lin, Yingcong, Guan, Qiaobing, Shen, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580360/
https://www.ncbi.nlm.nih.gov/pubmed/37269079
http://dx.doi.org/10.1111/cns.14290