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Katdetectr: an R/bioconductor package utilizing unsupervised changepoint analysis for robust kataegis detection
BACKGROUND: Kataegis refers to the occurrence of regional genomic hypermutation in cancer and is a phenomenon that has been observed in a wide range of malignancies. A kataegis locus constitutes a genomic region with a high mutation rate (i.e., a higher frequency of closely interspersed somatic vari...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580377/ https://www.ncbi.nlm.nih.gov/pubmed/37848617 http://dx.doi.org/10.1093/gigascience/giad081 |