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Marked Hypoleptinemia Precedes Overt Fat Loss in Immune Checkpoint Inhibitor-induced Acquired Generalized Lipodystrophy

Immune checkpoint inhibitors (ICIs) targeting cancer cells that evade immune T-cell regulation have revolutionized the treatment of metastatic carcinomas. Unfortunately, secondary endocrinopathies associated with ICI, including adrenal insufficiency, primary hypothyroidism, autoimmune diabetes, and...

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Detalles Bibliográficos
Autores principales: Dhanasekaran, Maheswaran, Sandooja, Rashi, Higgins, Alexandra S, Simha, Vinaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580409/
https://www.ncbi.nlm.nih.gov/pubmed/37908472
http://dx.doi.org/10.1210/jcemcr/luad025