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Effective Long-term Pediatric Pegvisomant Monotherapy to Final Height in X-linked Acrogigantism

X-linked acrogigantism (X-LAG) is characterized by extreme tall stature from early childhood resulting from duplication of the GPR101 gene, in turn resulting in GH excess. Most cases present with pituitary tumors secreting GH and prolactin. Diffuse pituitary hyperplasia is uncommon and normal prolac...

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Detalles Bibliográficos
Autores principales: Burren, Christine P, Williams, Georgina, Coxson, Edward, Korbonits, Márta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580488/
https://www.ncbi.nlm.nih.gov/pubmed/37908565
http://dx.doi.org/10.1210/jcemcr/luad028