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Genetic assessment of pathogenic germline alterations in lysosomal genes among Asian patients with pancreatic ductal adenocarcinoma

BACKGROUND: Lysosomes are closely linked to autophagic activity, which plays a vital role in pancreatic ductal adenocarcinoma (PDAC) biology. The survival of PDAC patients is still poor, and the identification of novel genetic factors for prognosis and treatment is highly required to prevent PDAC-re...

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Detalles Bibliográficos
Autores principales: Koh, Youngil, Kim, Hyemin, Joo, So Young, Song, Seulki, Choi, Young Hoon, Kim, Hyung Rae, Moon, Byul, Byun, Jamin, Hong, Junshik, Shin, Dong-Yeop, Park, Solip, Lee, Kwang Hyuck, Lee, Kyu Taek, Lee, Jong Kyun, Park, Daechan, Lee, Se-Hoon, Jang, Jin-Young, Lee, Hyunsook, Kim, Jung-Ae, Yoon, Sung-Soo, Park, Joo Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580633/
https://www.ncbi.nlm.nih.gov/pubmed/37848935
http://dx.doi.org/10.1186/s12967-023-04549-x