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Acellular ex vivo lung perfusate silences pro-inflammatory signaling in human lung endothelial and epithelial cells

BACKGROUND: Ischemia–reperfusion injury is a key complication following lung transplantation. The clinical application of ex vivo lung perfusion (EVLP) to assess donor lung function has significantly increased the utilization of “marginal” donor lungs with good clinical outcomes. The potential of EV...

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Detalles Bibliográficos
Autores principales: Jeon, Jamie E., Huang, Lei, Zhu, Zhiyuan, Wong, Aaron, Keshavjee, Shaf, Liu, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580637/
https://www.ncbi.nlm.nih.gov/pubmed/37845763
http://dx.doi.org/10.1186/s12967-023-04601-w