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A phosphodiesterase-4 inhibitor reduces lung inflammation and fibrosis in a hamster model of SARS-CoV-2 infection

INTRODUCTION: The Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) infection involves pulmonary inflammation that can progress to acute respiratory distress syndrome, a primary cause of lung damage/fibrosis in patients with Coronavirus Disease-2019 (COVID-19). Currently, there is no effi...

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Detalles Bibliográficos
Autores principales: Kolloli, Afsal, Ramasamy, Santhamani, Kumar, Ranjeet, Nisa, Annuurun, Kaplan, Gilla, Subbian, Selvakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580809/
https://www.ncbi.nlm.nih.gov/pubmed/37854602
http://dx.doi.org/10.3389/fimmu.2023.1270414