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Rv1453 is associated with clofazimine resistance in Mycobacterium tuberculosis

Clofazimine (CFZ) has been repurposed for treating tuberculosis (TB), especially multidrug-resistant tuberculosis (MDR-TB). However, the mechanisms of resistance to clofazimine are poorly understood. We previously reported a mutation located in the intergenic region of Rv1453 that was linked to resi...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Zhang, Ye, Li, Yuanyuan, Huo, Fengmin, Chen, Xi, Zhu, Hui, Guo, Shaochen, Fu, Lei, Wang, Bin, Lu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580819/
https://www.ncbi.nlm.nih.gov/pubmed/37615440
http://dx.doi.org/10.1128/spectrum.00002-23