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Rv1453 is associated with clofazimine resistance in Mycobacterium tuberculosis
Clofazimine (CFZ) has been repurposed for treating tuberculosis (TB), especially multidrug-resistant tuberculosis (MDR-TB). However, the mechanisms of resistance to clofazimine are poorly understood. We previously reported a mutation located in the intergenic region of Rv1453 that was linked to resi...
Autores principales: | Zhang, Lei, Zhang, Ye, Li, Yuanyuan, Huo, Fengmin, Chen, Xi, Zhu, Hui, Guo, Shaochen, Fu, Lei, Wang, Bin, Lu, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580819/ https://www.ncbi.nlm.nih.gov/pubmed/37615440 http://dx.doi.org/10.1128/spectrum.00002-23 |
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