Cargando…

Rv1453 is associated with clofazimine resistance in Mycobacterium tuberculosis

Clofazimine (CFZ) has been repurposed for treating tuberculosis (TB), especially multidrug-resistant tuberculosis (MDR-TB). However, the mechanisms of resistance to clofazimine are poorly understood. We previously reported a mutation located in the intergenic region of Rv1453 that was linked to resi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Lei, Zhang, Ye, Li, Yuanyuan, Huo, Fengmin, Chen, Xi, Zhu, Hui, Guo, Shaochen, Fu, Lei, Wang, Bin, Lu, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580819/ https://www.ncbi.nlm.nih.gov/pubmed/37615440 http://dx.doi.org/10.1128/spectrum.00002-23

Ejemplares similares

The Transcription Factor Rv1453 Regulates the Expression of qor and Confers Resistant to Clofazimine in Mycobacterium tuberculosis
por: Li, Yuanyuan, et al.
Publicado: (2021)

Bedaquiline- and clofazimine- selected Mycobacterium tuberculosis mutants: further insights on resistance driven largely by Rv0678
por: Snobre, J., et al.
Publicado: (2023)

Spontaneous mutational patterns and novel mutations for bedaquiline and clofazimine resistance in Mycobacterium tuberculosis
por: Shi, Jin, et al.
Publicado: (2023)

Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis
por: Sonnenkalb, Lindsay, et al.
Publicado: (2023)

Investigation of Clofazimine Resistance and Genetic Mutations in Drug-Resistant Mycobacterium tuberculosis Isolates
por: Park, Sanghee, et al.
Publicado: (2022)

Mycobacterium tuberculosis Rv0494 Protein Contributes to Mycobacterial Persistence
por: Ji, Lei, et al.
Publicado: (2023)

Clofazimine for the treatment of tuberculosis
por: Stadler, Jacob A. M., et al.
Publicado: (2023)

Evaluation of Rv0220, Rv2958c, Rv2994 and Rv3347c of Mycobacterium tuberculosis for serodiagnosis of tuberculosis
por: You, Xiaolong, et al.
Publicado: (2017)

Genetic and Virulence Characteristics of Linezolid and Pretomanid Dual Drug-Resistant Strains Induced from Mycobacterium tuberculosis in vitro
por: Hu, Minghao, et al.
Publicado: (2020)

Collated data of mutation frequencies and associated genetic variants of bedaquiline, clofazimine and linezolid resistance in Mycobacterium tuberculosis
por: Ismail, N., et al.
Publicado: (2018)

Clofazimine for Treatment of Mycobacterium abscessus Infections in Children
por: Adler-Shohet, Felice C, et al.
Publicado: (2017)

Role of Clofazimine in Treatment of Mycobacterium avium Complex
por: Nasiri, Mohammad Javad, et al.
Publicado: (2021)

Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis
por: Bolla, Jani Reddy, et al.
Publicado: (2012)

Transcription factors Rv0081 and Rv3334 connect the early and the enduring hypoxic response of Mycobacterium tuberculosis
por: Sun, Xian, et al.
Publicado: (2018)

Triclosan-induced genes Rv1686c-Rv1687c and Rv3161c are not involved in triclosan resistance in Mycobacterium tuberculosis
por: Gomez, Andromeda, et al.
Publicado: (2016)

Circularization of rv0678 for Genotypic Bedaquiline Resistance Testing of Mycobacterium tuberculosis
por: Limberis, Jason D., et al.
Publicado: (2023)

Investigation of the Rv3065, Rv2942, Rv1258c, Rv1410c, and Rv2459 efflux pump genes expression among multidrug-resistant Mycobacterium tuberculosis clinical isolates
por: Shahi, Fatemeh, et al.
Publicado: (2021)

Novel Administration of Clofazimine for the Treatment of Mycobacterium avium Infection
por: Valinetz, Ethan, et al.
Publicado: (2020)

Epidemiology of Nontuberculous Mycobacteria in Nanjing and MAB_0540 Mutations Associated with Clofazimine Resistance in Mycobacterium abscessus
por: Zhang, Ruixian, et al.
Publicado: (2023)

Rv2031c of Mycobacterium tuberculosis: a master regulator of Rv2028–Rv2031 (HspX) operon
por: Mushtaq, Khurram, et al.
Publicado: (2015)

Mycobacterium tuberculosis H37Rv infection regulates alternative splicing in Macrophages
por: Zhang, Wei, et al.
Publicado: (2018)

Rv3722c Promotes Mycobacterium tuberculosis Survival in Macrophages by Interacting With TRAF3
por: Lei, Yingying, et al.
Publicado: (2021)

Deletion of Rv2571c Confers Resistance to Arylamide Compounds in Mycobacterium tuberculosis
por: Shelton, Catherine D., et al.
Publicado: (2021)

In vitro modeling of isoniazid resistance mechanisms in Mycobacterium tuberculosis H37Rv
por: Dokrungkoon, Thanadon, et al.
Publicado: (2023)

Pyrazinoic Acid Inhibits the Bifunctional Enzyme (Rv2783) in Mycobacterium tuberculosis by Competing with tmRNA
por: He, Lei, et al.
Publicado: (2019)

Acquisition of Cross-Resistance to Bedaquiline and Clofazimine following Treatment for Tuberculosis in Pakistan
por: Ghodousi, Arash, et al.
Publicado: (2019)

Network analysis identifies Rv0324 and Rv0880 as regulators of bedaquiline tolerance in Mycobacterium tuberculosis
por: Peterson, Eliza J.R., et al.
Publicado: (2016)

Unexpected high prevalence of resistance-associated Rv0678 variants in MDR-TB patients without documented prior use of clofazimine or bedaquiline
por: Villellas, Cristina, et al.
Publicado: (2017)

Mycobacterium tuberculosis Rv0309 Dampens the Inflammatory Response and Enhances Mycobacterial Survival
por: Peng, Yongchong, et al.
Publicado: (2022)

Antigens Rv0310c and Rv1255c are promising novel biomarkers for the diagnosis of Mycobacterium tuberculosis infection
por: Luo, Liulin, et al.
Publicado: (2017)

Rv2629 Overexpression Delays Mycobacterium smegmatis and Mycobacteria tuberculosis Entry into Log-Phase and Increases Pathogenicity of Mycobacterium smegmatis in Mice
por: Liu, Dan, et al.
Publicado: (2017)

Humoral Responses to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR Regulon-Encoded Proteins of Mycobacterium tuberculosis in Individuals with Latent Tuberculosis Infection
por: Kimuda, Simon G., et al.
Publicado: (2017)

Enhanced serodiagnostic potential of a fusion molecule consisting of Rv1793, Rv2628 and a truncated Rv2608 of Mycobacterium tuberculosis
por: Sulman, Sadaf, et al.
Publicado: (2021)

Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis
por: Zhao, Nan, et al.
Publicado: (2015)

Bedaquiline, Delamanid, Linezolid, and Clofazimine for Treatment of Pre-extensively Drug-Resistant Tuberculosis
por: Padmapriyadarsini, Chandrasekaran, et al.
Publicado: (2022)

First report of whole-genome analysis of an extensively drug-resistant Mycobacterium tuberculosis clinical isolate with bedaquiline, linezolid and clofazimine resistance from Uganda
por: Kabahita, Jupiter Marina, et al.
Publicado: (2022)

Improved outcomes following addition of bedaquiline and clofazimine to a treatment regimen for multidrug-resistant tuberculosis
por: Yao, Ge, et al.
Publicado: (2023)

Varying effects of common tuberculosis drugs on enhancing clofazimine activity in vitro
por: Zhang, Shuo, et al.
Publicado: (2017)

Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis
por: Zheng, Xiangdong, et al.
Publicado: (2011)

Regulation of CRISPR-Associated Genes by Rv1776c (CasR) in Mycobacterium tuberculosis
por: Wei, Wenping, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_k7v09dcbag6le7cbjkd0gaitb4