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ATG9A supports Chlamydia trachomatis infection via autophagy-independent mechanisms

Chlamydia trachomatis infection can be regulated by autophagy-related (ATG) genes. Here, we found that the depletion of ATG9A, one of the core ATG genes, in HeLa cells suppressed C. trachomatis growth in the inclusion. The growth was restored by re-expressing ATG9A or an ATG9A mutant impairing lipid...

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Detalles Bibliográficos
Autores principales: Suzuki, Michitaka, Funakoshi, Tomoko, Kumagai, Keigo, Komatsu, Masaaki, Waguri, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580829/
https://www.ncbi.nlm.nih.gov/pubmed/37707289
http://dx.doi.org/10.1128/spectrum.02774-23