AMPK protects endothelial cells against HSV-1 replication via inhibition of mTORC1 and ACC1

Herpes simplex virus type 1 (HSV-1) is a widespread contagious pathogen, mostly causing mild symptoms on the mucosal entry side. However, systemic distribution, in particular upon reactivation of the virus in immunocompromised patients, may trigger an innate immune response and induce damage of orga...

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Detalles Bibliográficos
Autores principales: Doshi, Heena, Spengler, Katrin, Godbole, Amod, Gee, Yi Sing, Baell, Jonathan, Oakhill, Jonathan S., Henke, Andreas, Heller, Regine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580915/
https://www.ncbi.nlm.nih.gov/pubmed/37702499
http://dx.doi.org/10.1128/spectrum.00417-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580915/
https://www.ncbi.nlm.nih.gov/pubmed/37702499
http://dx.doi.org/10.1128/spectrum.00417-23

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