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AMPK protects endothelial cells against HSV-1 replication via inhibition of mTORC1 and ACC1
Herpes simplex virus type 1 (HSV-1) is a widespread contagious pathogen, mostly causing mild symptoms on the mucosal entry side. However, systemic distribution, in particular upon reactivation of the virus in immunocompromised patients, may trigger an innate immune response and induce damage of orga...
Autores principales: | Doshi, Heena, Spengler, Katrin, Godbole, Amod, Gee, Yi Sing, Baell, Jonathan, Oakhill, Jonathan S., Henke, Andreas, Heller, Regine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580915/ https://www.ncbi.nlm.nih.gov/pubmed/37702499 http://dx.doi.org/10.1128/spectrum.00417-23 |
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