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Control of Helicobacter pylori with engineered probiotics secreting selective guided antimicrobial peptides

Helicobacter pylori is the primary cause of 78% of gastric cancer cases, providing an opportunity to prevent cancer by controlling a single bacterial pathogen within the complex gastric microbiota. We developed highly selective antimicrobial agents against H. pylori by fusing an H. pylori-binding gu...

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Detalles Bibliográficos
Autores principales: Choudhury, Ankan, Ortiz, Patrick S., Young, Mikaeel, Mahmud, Md. Toslim, Stoffel, Ryan T., Greathouse, K. Leigh, Kearney, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580918/
https://www.ncbi.nlm.nih.gov/pubmed/37712669
http://dx.doi.org/10.1128/spectrum.02014-23