Erythronate utilization activates VdtR regulating its metabolism to promote Brucella proliferation, inducing abortion in mice

Brucella is a facultative intracellular pathogen that preferentially colonizes reproductive organs and utilizes erythritol as a preferred carbon source for its survival and proliferation. In this study, we identified a virulence-related DeoR-family transcriptional regulator (VdtR) and an erythronate...

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Detalles Bibliográficos
Autores principales: Yin, Yi, Fang, Tian, Lian, Zhengmin, Zuo, Dong, Hu, Hai, Zhang, Guangdong, Ding, Chan, Tian, Mingxing, Yu, Shengqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580937/
https://www.ncbi.nlm.nih.gov/pubmed/37671873
http://dx.doi.org/10.1128/spectrum.02074-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580937/
https://www.ncbi.nlm.nih.gov/pubmed/37671873
http://dx.doi.org/10.1128/spectrum.02074-23

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