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Proteasome inhibition as a therapeutic target for the fungal pathogen Cryptococcus neoformans

The current therapeutic challenges for treating fungal diseases demand new approaches and new drugs. A promising strategy involves combination therapy with agents of distinct mechanisms of action to increase fungicidal activity and limit the impact of mutations leading to resistance. In this study,...

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Detalles Bibliográficos
Autores principales: Caza, Mélissa, Santos, Daniel Assis, Burden, Elizabeth, Brisland, Anna, Hu, Guanggan, Kronstad, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580939/
https://www.ncbi.nlm.nih.gov/pubmed/37750732
http://dx.doi.org/10.1128/spectrum.01904-23