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In vitro and intracellular activities of novel thiopeptide derivatives against macrolide-susceptible and macrolide-resistant Mycobacterium avium complex

Unsatisfactory outcomes following long-term multidrug treatment in patients with Mycobacterium avium complex (MAC) pulmonary disease have urged us to develop novel antibiotics. Thiopeptides, a class of peptide antibiotics derived from natural products, have potential as drug candidates that target b...

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Detalles Bibliográficos
Autores principales: Park, Jiyun, Kim, Lee-Han, Lee, Ju Mi, Choi, Sangwon, Son, Young-Jin, Hwang, Hee-Jong, Shin, Sung Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580953/
https://www.ncbi.nlm.nih.gov/pubmed/37594284
http://dx.doi.org/10.1128/spectrum.01825-23