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Streptomyces albidoflavus Q antifungal metabolites inhibit the ergosterol biosynthesis pathway and yeast growth in fluconazole-resistant Candida glabrata: phylogenomic and metabolomic analyses

There is an urgent need to develop new antifungals due to the increasing prevalence of multidrug-resistant fungal infections and the recent emergence of COVID-19-associated candidiasis. A good study model for evaluating new antifungal compounds is Candida glabrata, an opportunistic fungal pathogen w...

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Detalles Bibliográficos
Autores principales: Bautista-Crescencio, Celia, Casimiro-Ramos, Arturo, Fragoso-Vázquez, M. Jonathan, Correa-Basurto, José, Olano, Carlos, Hernández-Rodríguez, César, Villa-Tanaca, Lourdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581079/
https://www.ncbi.nlm.nih.gov/pubmed/37754674
http://dx.doi.org/10.1128/spectrum.01271-23