Cargando…
Streptomyces albidoflavus Q antifungal metabolites inhibit the ergosterol biosynthesis pathway and yeast growth in fluconazole-resistant Candida glabrata: phylogenomic and metabolomic analyses
There is an urgent need to develop new antifungals due to the increasing prevalence of multidrug-resistant fungal infections and the recent emergence of COVID-19-associated candidiasis. A good study model for evaluating new antifungal compounds is Candida glabrata, an opportunistic fungal pathogen w...
Autores principales: | Bautista-Crescencio, Celia, Casimiro-Ramos, Arturo, Fragoso-Vázquez, M. Jonathan, Correa-Basurto, José, Olano, Carlos, Hernández-Rodríguez, César, Villa-Tanaca, Lourdes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581079/ https://www.ncbi.nlm.nih.gov/pubmed/37754674 http://dx.doi.org/10.1128/spectrum.01271-23 |
Ejemplares similares
-
Antifungal Activity of Fibrate-Based Compounds and Substituted Pyrroles That Inhibit the Enzyme 3-Hydroxy-methyl-glutaryl-CoA Reductase of Candida glabrata (CgHMGR), Thus Decreasing Yeast Viability and Ergosterol Synthesis
por: Madrigal-Aguilar, Damián A., et al.
Publicado: (2022) -
Synergistic effects of tacrolimus and azole antifungal compounds in fluconazole-susceptible and fluconazole-resistant Candida glabrata
isolates
por: Denardi, Laura Bedin, et al.
Publicado: (2015) -
Evaluation of antifungal activity of mint, pomegranate and coriander on fluconazole-resistant Candida glabrata
por: Jayan, Lekshmy, et al.
Publicado: (2020) -
Candida glabrata Transcription Factor Rpn4 Mediates Fluconazole Resistance through Regulation of Ergosterol Biosynthesis and Plasma Membrane Permeability
por: Pais, Pedro, et al.
Publicado: (2020) -
Limosilactobacillus fermentum Limits Candida glabrata Growth by Ergosterol Depletion
por: Zangl, Isabella, et al.
Publicado: (2023)