Structural biology and functional features of phage-derived depolymerase Depo32 on Klebsiella pneumoniae with K2 serotype capsular polysaccharides

Hypervirulent Klebsiella pneumoniae with capsular polysaccharides (CPSs) causes severe nosocomial- and community-acquired infections. Phage-derived depolymerases can degrade CPSs from K. pneumoniae to attenuate bacterial virulence, but their antimicrobial mechanisms and clinical potential are not we...

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Detalles Bibliográficos
Autores principales: Cai, Ruopeng, Ren, Zhuolu, Zhao, Rihong, Lu, Yan, Wang, Xinwu, Guo, Zhimin, Song, Jinming, Xiang, Wentao, Du, Rui, Zhang, Xiaokang, Han, Wenyu, Ru, Heng, Gu, Jingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581125/
https://www.ncbi.nlm.nih.gov/pubmed/37750730
http://dx.doi.org/10.1128/spectrum.05304-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581125/
https://www.ncbi.nlm.nih.gov/pubmed/37750730
http://dx.doi.org/10.1128/spectrum.05304-22

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