Viral and cellular telomerase RNAs possess host-specific anti-apoptotic functions

Human telomerase RNA (hTR) is overexpressed in many cancers and protects T cells from apoptosis in a telomerase-independent manner. The most prevalent cancer in the animal kingdom is caused by the highly oncogenic herpesvirus Marek’s disease virus (MDV). MDV encodes a viral telomerase RNA (vTR) that...

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Detalles Bibliográficos
Autores principales: Kheimar, Ahmed, Trapp-Fragnet, Laetitia, Conradie, Andelé M., Bertzbach, Luca D., You, Yu, Sabsabi, Mohammad A., Kaufer, Benedikt B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581129/
https://www.ncbi.nlm.nih.gov/pubmed/37754662
http://dx.doi.org/10.1128/spectrum.01887-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581129/
https://www.ncbi.nlm.nih.gov/pubmed/37754662
http://dx.doi.org/10.1128/spectrum.01887-23

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