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Viral and cellular telomerase RNAs possess host-specific anti-apoptotic functions

Human telomerase RNA (hTR) is overexpressed in many cancers and protects T cells from apoptosis in a telomerase-independent manner. The most prevalent cancer in the animal kingdom is caused by the highly oncogenic herpesvirus Marek’s disease virus (MDV). MDV encodes a viral telomerase RNA (vTR) that...

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Detalles Bibliográficos
Autores principales:	Kheimar, Ahmed, Trapp-Fragnet, Laetitia, Conradie, Andelé M., Bertzbach, Luca D., You, Yu, Sabsabi, Mohammad A., Kaufer, Benedikt B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581129/ https://www.ncbi.nlm.nih.gov/pubmed/37754662 http://dx.doi.org/10.1128/spectrum.01887-23

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