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In vivo efficacy of pitavastatin combined with itraconazole against Aspergillus fumigatus in silkworm models

Azole resistance in Aspergillus fumigatus is a worldwide concern and new antifungal drugs are required to overcome this problem. Statin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, has been reported to suppress the growth of A. fumigatus, but little is known about its in v...

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Detalles Bibliográficos
Autores principales: Majima, Hidetaka, Arai, Teppei, Kamei, Katsuhiko, Watanabe, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581172/
https://www.ncbi.nlm.nih.gov/pubmed/37655910
http://dx.doi.org/10.1128/spectrum.02666-23