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Tezacaftor/Ivacaftor therapy has negligible effects on the cystic fibrosis gut microbiome

People with cystic fibrosis (pwCF) experience a range of persistent gastrointestinal symptoms throughout life. There is evidence indicating interaction between the microbiota and gut pathophysiology in CF. However, there is a paucity of knowledge on the potential effects of CF transmembrane conducta...

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Detalles Bibliográficos
Autores principales: Marsh, Ryan, Dos Santos, Claudio, Hanson, Liam, Ng, Christabella, Major, Giles, Smyth, Alan R., Rivett, Damian, van der Gast, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581179/
https://www.ncbi.nlm.nih.gov/pubmed/37607068
http://dx.doi.org/10.1128/spectrum.01175-23