Discovery of novel reversible inhibitor of DprE1 based on benzomorpholine for the treatment of tuberculosis

About a quarter of the world’s population is infected with Mycobacterium tuberculosis, equivalent to about two billion people. With the emergence of multidrug-resistant tuberculosis, those existing anti-tuberculosis drugs no longer meet the demand for cure anymore; there is an urgent need for the de...

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Detalles Bibliográficos
Autores principales: Xiang, Wang, He, Hualong, Duan, Xianjie, He, Zhiqun, Xu, Xinyue, Liao, Mengya, Teng, Fei, Li, Xiao, Luo, Tianwen, Zeng, Jumei, Yu, Luoting, Gao, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581193/
https://www.ncbi.nlm.nih.gov/pubmed/37698416
http://dx.doi.org/10.1128/spectrum.04721-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581193/
https://www.ncbi.nlm.nih.gov/pubmed/37698416
http://dx.doi.org/10.1128/spectrum.04721-22

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