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Discovery of novel reversible inhibitor of DprE1 based on benzomorpholine for the treatment of tuberculosis
About a quarter of the world’s population is infected with Mycobacterium tuberculosis, equivalent to about two billion people. With the emergence of multidrug-resistant tuberculosis, those existing anti-tuberculosis drugs no longer meet the demand for cure anymore; there is an urgent need for the de...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581193/ https://www.ncbi.nlm.nih.gov/pubmed/37698416 http://dx.doi.org/10.1128/spectrum.04721-22 |