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Interactive effects between CDHR3 genotype and rhinovirus species for diagnosis and severity of respiratory tract infections in hospitalized children

Rhinovirus (RV) is the leading pathogen causing childhood wheezing, with rhinovirus C (RV-C) species reported to cause asthma exacerbation. Allele A of single-nucleotide polymorphism (SNP) CDHR3_rs6967330 upregulates epithelial expression of RV-C receptors which results in more severe asthma exacerb...

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Detalles Bibliográficos
Autores principales: Song, Yu P., Tang, Man F., Leung, Agnes S. Y., Tao, Kin P., Chan, Oi M., Wong, Gary W. K., Chan, Paul K. S., Chan, Renee W. Y., Leung, Ting F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581227/
https://www.ncbi.nlm.nih.gov/pubmed/37750685
http://dx.doi.org/10.1128/spectrum.01181-23