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Protocol and statistical analysis plan for the mega randomised registry trial comparing conservative vs. liberal oxygenation targets in adults with nonhypoxic ischaemic acute brain injuries and conditions in the intensive care unit (Mega-ROX Brains)

BACKGROUND: The effect of conservative vs. liberal oxygen therapy on 90-day in-hospital mortality in adults who have nonhypoxic ischaemic encephalopathy acute brain injuries and conditions and are receiving invasive mechanical ventilation in the intensive care unit (ICU) is uncertain. OBJECTIVE: The...

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Detalles Bibliográficos
Autores principales: Young, Paul J., Al-Fares, Abdulrahman, Aryal, Diptesh, Arabi, Yaseen M., Ashraf, Muhammad Sheharyar, Bagshaw, Sean M., Mat-Nor, Mohd Basri, Beane, Abigail, Borghi, Giovanni, de Oliveira Manoel, Airton L., Dullawe, Layoni, Fazla, Fathima, Fujii, Tomoko, Haniffa, Rashan, Hodgson, Carol L., Hunt, Anna, Lawrence, Cassie, Mackle, Diane, Mangal, Kishore, Nichol, Alistair D., Olatunji, Shaanti, Rashan, Aasiyah, Rashan, Sumayyah, Tomazini, Bruno, Kasza, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581272/
https://www.ncbi.nlm.nih.gov/pubmed/37876994
http://dx.doi.org/10.1016/j.ccrj.2023.04.011