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The Largest Chinese Cohort Study Indicates Homologous Recombination Pathway Gene Mutations as Another Major Genetic Risk Factor for Colorectal Cancer with Heterogeneous Clinical Phenotypes

While genetic factors were associated with over 30% of colorectal cancer (CRC) patients, mutations in CRC-susceptibility genes were identified in only 5% to 10% of these patients. Besides, previous studies on hereditary CRC were largely designed to analyze germline mutations in patients with single...

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Detalles Bibliográficos
Autores principales: Xu, Yun, Liu, Kai, Li, Cong, Li, Minghan, Liu, Fangqi, Zhou, Xiaoyan, Sun, Menghong, Ranganathan, Megha, Zhang, Liying, Wang, Sheng, Hu, Xin, Xu, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581333/
https://www.ncbi.nlm.nih.gov/pubmed/37854294
http://dx.doi.org/10.34133/research.0249