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The Largest Chinese Cohort Study Indicates Homologous Recombination Pathway Gene Mutations as Another Major Genetic Risk Factor for Colorectal Cancer with Heterogeneous Clinical Phenotypes
While genetic factors were associated with over 30% of colorectal cancer (CRC) patients, mutations in CRC-susceptibility genes were identified in only 5% to 10% of these patients. Besides, previous studies on hereditary CRC were largely designed to analyze germline mutations in patients with single...
Autores principales: | Xu, Yun, Liu, Kai, Li, Cong, Li, Minghan, Liu, Fangqi, Zhou, Xiaoyan, Sun, Menghong, Ranganathan, Megha, Zhang, Liying, Wang, Sheng, Hu, Xin, Xu, Ye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAAS
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581333/ https://www.ncbi.nlm.nih.gov/pubmed/37854294 http://dx.doi.org/10.34133/research.0249 |
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