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Sodium butyrate does not protect spinal motor neurons from AMPA-induced excitotoxic degeneration in vivo
Motor neuron (MN) loss is the primary pathological hallmark of amyotrophic lateral sclerosis (ALS). Histone deacetylase 4 (HDAC4) is one of several factors involved in nerve–muscle communication during MN loss, hindering muscle reinnervation, as shown in humans and in animal models of ALS, and may e...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581382/ https://www.ncbi.nlm.nih.gov/pubmed/37756598 http://dx.doi.org/10.1242/dmm.049851 |