Cargando…

Sodium butyrate does not protect spinal motor neurons from AMPA-induced excitotoxic degeneration in vivo

Motor neuron (MN) loss is the primary pathological hallmark of amyotrophic lateral sclerosis (ALS). Histone deacetylase 4 (HDAC4) is one of several factors involved in nerve–muscle communication during MN loss, hindering muscle reinnervation, as shown in humans and in animal models of ALS, and may e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prior-González, Mara, Lazo-Gómez, Rafael, Tapia, Ricardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581382/ https://www.ncbi.nlm.nih.gov/pubmed/37756598 http://dx.doi.org/10.1242/dmm.049851

Ejemplares similares

Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates
por: Netzahualcoyotzi, Citlalli, et al.
Publicado: (2015)

Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism
por: Lazo-Gomez, Rafael, et al.
Publicado: (2017)

Role of energy metabolic deficits and oxidative stress in excitotoxic spinal motor neuron degeneration in vivo
por: Santa-Cruz, Luz Diana, et al.
Publicado: (2014)

Histone deacetylases and their role in motor neuron degeneration
por: Lazo-Gómez, Rafael, et al.
Publicado: (2013)

Inducing Chronic Excitotoxicity in the Mouse Spinal Cord to Investigate Lower Motor Neuron Degeneration
por: Blizzard, Catherine A., et al.
Publicado: (2016)

Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo
por: Netzahualcoyotzi, Citlalli, et al.
Publicado: (2018)

Calcium Permeable-AMPA Receptors and Excitotoxicity in Neurological Disorders
por: Guo, Changyong, et al.
Publicado: (2021)

Delayed administration of VEGF rescues spinal motor neurons from death with a short effective time frame in excitotoxic experimental models in vivo
por: Tovar-y-Romo, Luis B, et al.
Publicado: (2012)

C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca(2+)-permeable AMPA receptor-mediated excitotoxicity
por: Selvaraj, Bhuvaneish T., et al.
Publicado: (2018)

Motor Alterations Induced by Chronic 4-Aminopyridine Infusion in the Spinal Cord In vivo: Role of Glutamate and GABA Receptors
por: Lazo-Gómez, Rafael, et al.
Publicado: (2016)

GABA Receptor Agonists Protect From Excitotoxic Damage Induced by AMPA in Oligodendrocytes
por: Bayón-Cordero, Laura, et al.
Publicado: (2022)

Mutant prion proteins increase calcium permeability of AMPA receptors, exacerbating excitotoxicity
por: Ghirardini, Elsa, et al.
Publicado: (2020)

Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration
por: Pozniak, Christine D., et al.
Publicado: (2013)

Correction: Mutant prion proteins increase calcium permeability of AMPA receptors, exacerbating excitotoxicity
por: Ghirardini, Elsa, et al.
Publicado: (2020)

Trophic factors as modulators of motor neuron physiology and survival: implications for ALS therapy
por: Tovar-y-Romo, Luis B., et al.
Publicado: (2014)

Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity
por: Brockington, Alice, et al.
Publicado: (2012)

AMPA Receptor Phosphorylation and Synaptic Colocalization on Motor Neurons Drive Maladaptive Plasticity below Complete Spinal Cord Injury
por: Huie, J. Russell, et al.
Publicado: (2015)

Translatomic analysis of regenerating and degenerating spinal motor neurons in injury and ALS
por: Shadrach, Jennifer L., et al.
Publicado: (2021)

The Effects of Sodium Butyrate, Coated Sodium Butyrate, and Butyric Acid Glycerides on Nutrient Digestibility, Gastrointestinal Function, and Fecal Microbiota in Turkeys
por: Makowski, Zbigniew, et al.
Publicado: (2022)

Dibutyryl Cyclic Adenosine Monophosphate Rescues the Neurons From Degeneration in Stab Wound and Excitotoxic Injury Models
por: Abd-El-Basset, Ebtesam M., et al.
Publicado: (2018)

NSC-34 Motor Neuron-Like Cells Are Unsuitable as Experimental Model for Glutamate-Mediated Excitotoxicity
por: Madji Hounoum, Blandine, et al.
Publicado: (2016)

Limitations and Challenges in Modeling Diseases Involving Spinal Motor Neuron Degeneration in Vitro
por: Bucchia, Monica, et al.
Publicado: (2018)

Regulation of AMPA receptors in spinal nociception
por: Wang, Yun, et al.
Publicado: (2010)

Influences of the circadian clock on neuronal susceptibility to excitotoxicity
por: Karmarkar, Sumedha W., et al.
Publicado: (2013)

Superoxide and Non-ionotropic Signaling in Neuronal Excitotoxicity
por: Wang, Jiejie, et al.
Publicado: (2020)

BMP4 Is a Peripherally-Derived Factor for Motor Neurons and Attenuates Glutamate-Induced Excitotoxicity In Vitro
por: Chou, Hui-Ju, et al.
Publicado: (2013)

Identifying the primary site of pathogenesis in amyotrophic lateral sclerosis – vulnerability of lower motor neurons to proximal excitotoxicity
por: Blizzard, Catherine A., et al.
Publicado: (2015)

Effect of sodium butyrate on lymphocyte activation
por: Kyner, D, et al.
Publicado: (1976)

C9orf72 ablation in mice does not cause motor neuron degeneration or motor deficits
por: Koppers, Max, et al.
Publicado: (2015)

Molecular constituents of neuronal AMPA receptors
por: Fukata, Yuko, et al.
Publicado: (2005)

PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons
por: Yang, D-J, et al.
Publicado: (2014)

Riluzole But Not Melatonin Ameliorates Acute Motor Neuron Degeneration and Moderately Inhibits SOD1-Mediated Excitotoxicity Induced Disrupted Mitochondrial Ca(2+) Signaling in Amyotrophic Lateral Sclerosis
por: Jaiswal, Manoj Kumar
Publicado: (2017)

Dopamine protects neurons against glutamate-induced excitotoxicity
por: Vaarmann, A, et al.
Publicado: (2013)

Differentiation renders susceptibility to excitotoxicity in HT22 neurons☆
por: He, Minchao, et al.
Publicado: (2013)

Effect of Pioglitazone on Excitotoxic Neuronal Damage in the Mouse Hippocampus
por: Lee, Choong Hyun, et al.
Publicado: (2015)

Insulin Protects Cortical Neurons Against Glutamate Excitotoxicity
por: Krasil’nikova, Irina, et al.
Publicado: (2019)

Delivering progranulin to neuronal lysosomes protects against excitotoxicity
por: Davis, Skylar E., et al.
Publicado: (2021)

Isoliquiritigenin Protects Neuronal Cells against Glutamate Excitotoxicity
por: Zgodova, Arina, et al.
Publicado: (2022)

Preventive and Therapeutic Autoantibodies Protect against Neuronal Excitotoxicity
por: Zhou, Xianjin
Publicado: (2023)

Neuronal VPS35 deletion induces spinal cord motor neuron degeneration and early post-natal lethality
por: Sargent, Dorian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j78k5lr18484jh4p5heogvr12b