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Tyrosine kinase receptor B attenuates liver fibrosis by inhibiting TGF-β/SMAD signaling

BACKGROUND AND AIMS: Liver fibrosis is a leading indicator for increased mortality and long-term comorbidity in NASH. Activation of HSCs and excessive extracellular matrix production are the hallmarks of liver fibrogenesis. Tyrosine kinase receptor (TrkB) is a multifunctional receptor that participa...

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Detalles Bibliográficos
Autores principales: Song, Yu, Wei, Jiayi, Li, Rong, Fu, Ruifeng, Han, Pei, Wang, Heming, Zhang, Guangcong, Li, Shuyu, Chen, Sinuo, Liu, Zhiyong, Zhao, Yicheng, Zhu, Changfeng, Zhu, Jimin, Zhang, Shuncai, Pei, Hao, Cheng, Jiefei, Wu, Jian, Dong, Ling, Song, Guangqi, Shen, Xizhong, Yao, Qunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581422/
https://www.ncbi.nlm.nih.gov/pubmed/36800849
http://dx.doi.org/10.1097/HEP.0000000000000319