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Rosiglitazone-Mediated Activation of PPARγ Restores HO1 Expression in the Human Preeclamptic Placenta

BACKGROUND: Preeclampsia is a hypertensive disorder of pregnancy characterized by chronic placental ischemia and suppression of proangiogenic proteins, causing oxidative stress, hypertension, and maternal systemic organ damage. The transcription factor, PPARγ (peroxisome proliferator-activated recep...

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Detalles Bibliográficos
Autores principales: Grimaldi, Brooke, Kohan-Ghadr, Hamid-Reza, Halari, Chidambra D., Nandi, Pinki, Kingdom, John C., Drewlo, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581437/
https://www.ncbi.nlm.nih.gov/pubmed/37702083
http://dx.doi.org/10.1161/HYPERTENSIONAHA.123.21645