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Contribution of Spontaneous Mutations to Quantitative and Molecular Variation at the Highly Repetitive rDNA Locus in Yeast

The ribosomal DNA array in Saccharomyces cerevisiae consists of many tandem repeats whose copy number is believed to be functionally important but highly labile. Regulatory mechanisms have evolved to maintain copy number by directed mutation, but how spontaneous variation at this locus is generated...

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Detalles Bibliográficos
Autores principales: Sharp, Nathaniel P, Smith, Denise R, Driscoll, Gregory, Sun, Kexin, Vickerman, Catherine M, Martin, Sterling C T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581546/
https://www.ncbi.nlm.nih.gov/pubmed/37847861
http://dx.doi.org/10.1093/gbe/evad179