Retrospective Cohort Study on the Limitations of Direct-to-Consumer Genetic Screening in Hereditary Breast and Ovarian Cancer

PURPOSE: Among cancer predisposition genes, most direct-to-consumer (DTC) genetic tests evaluate three Ashkenazi Jewish (AJ) founder mutations in BRCA1/2, which represent a small proportion of pathogenic or likely pathogenic variants (PLPV) in cancer predisposing genes. In this study, we investigate...

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Detalles Bibliográficos
Autores principales: Desai, Neelam V., Barrows, Elizabeth D., Nielsen, Sarah M., Hatchell, Kathryn E., Anderson, Michael J., Haverfield, Eden V., Herrera, Blanca, Esplin, Edward D., Lucassen, Anneke, Tung, Nadine M., Isaacs, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581610/
https://www.ncbi.nlm.nih.gov/pubmed/37535880
http://dx.doi.org/10.1200/PO.22.00695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581610/
https://www.ncbi.nlm.nih.gov/pubmed/37535880
http://dx.doi.org/10.1200/PO.22.00695

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