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Comprehensive Analysis of Human Epidermal Growth Factor Receptor 2 Through DNA, mRNA, and Protein in Diverse Malignancies

PURPOSE: Human epidermal growth factor receptor 2 (HER2) expression (protein immunohistochemistry [IHC] or gene amplification [copy-number variation, CNV]) predicts anti-HER2 therapy responsiveness, although recently it was shown that even low HER2-expressing breast cancers benefit from trastuzumab-...

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Detalles Bibliográficos
Autores principales: Shayeb, Akram Mesleh, Kurzrock, Razelle, Adashek, Jacob J., Kato, Shumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581650/
https://www.ncbi.nlm.nih.gov/pubmed/37437231
http://dx.doi.org/10.1200/PO.22.00604