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Transglutaminase 2 is associated with adverse colorectal cancer survival and represents a therapeutic target

Molecular markers for predicting prognosis of colorectal cancer (CRC) patients are urgently needed for effective disease management. We reported previously that the multifunctional enzyme Transglutaminase 2 (TGM2) is essential for CRC cell survival by inactivation of the tumor suppressor p53. Based...

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Detalles Bibliográficos
Autores principales: Malkomes, Patrizia, Lunger, Ilaria, Oppermann, Elsie, Lorenz, Johannes, Faqar-Uz-Zaman, Sara Fatima, Han, Jiaoyan, Bothur, Sabrina, Ziegler, Paul, Bankov, Katrin, Wild, Peter, Bechstein, Wolf Otto, Rieger, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581896/
https://www.ncbi.nlm.nih.gov/pubmed/37443286
http://dx.doi.org/10.1038/s41417-023-00641-y