Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches

BACKGROUND AND OBJECTIVES: Vericiguat is a soluble guanylate cyclase stimulator indicated to reduce the risk of cardiovascular death and hospitalization due to heart failure. A dedicated QTc study in patients with chronic coronary syndromes demonstrated no clinically relevant QTc effect of vericigua...

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Detalles Bibliográficos
Autores principales: Ruehs, Hauke, Solms, Alexander, Frei, Matthias, Becker, Corina, Trujillo, Maria E., Garmann, Dirk, Meyer, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581916/
https://www.ncbi.nlm.nih.gov/pubmed/37672197
http://dx.doi.org/10.1007/s40262-023-01282-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581916/
https://www.ncbi.nlm.nih.gov/pubmed/37672197
http://dx.doi.org/10.1007/s40262-023-01282-y

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