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Neuronal RBM5 modulates cell signaling responses to traumatic and hypoxic-ischemic injury in a sex-dependent manner

It is not clear if inhibiting the pro-death gene RNA binding motif 5 (RBM5) is neuroprotective in isolated primary neurons or if it regulates cell survival in a sex-dependent manner. Here we established sex-dichotomized primary cortical neuron cultures from transgenic mice harboring a floxed RBM5 ge...

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Detalles Bibliográficos
Autores principales: Snyder, Kara, Gorse, Kiersten, Kochanek, Patrick M., Jackson, Travis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582027/
https://www.ncbi.nlm.nih.gov/pubmed/37848418
http://dx.doi.org/10.1038/s41420-023-01677-7