Cargando…

Neuronal RBM5 modulates cell signaling responses to traumatic and hypoxic-ischemic injury in a sex-dependent manner

It is not clear if inhibiting the pro-death gene RNA binding motif 5 (RBM5) is neuroprotective in isolated primary neurons or if it regulates cell survival in a sex-dependent manner. Here we established sex-dichotomized primary cortical neuron cultures from transgenic mice harboring a floxed RBM5 ge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Snyder, Kara, Gorse, Kiersten, Kochanek, Patrick M., Jackson, Travis C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582027/ https://www.ncbi.nlm.nih.gov/pubmed/37848418 http://dx.doi.org/10.1038/s41420-023-01677-7

Ejemplares similares

Robust RBM3 and β-klotho expression in developing neurons in the human brain
por: Jackson, Travis C, et al.
Publicado: (2019)

Hippocampal and Prefrontal Cortical Brain Tissue Levels of Irisin and GDF15 Receptor Subunits in Children
por: Jackson, Travis C., et al.
Publicado: (2021)

RBM3 promotes neurogenesis in a niche-dependent manner via IMP2-IGF2 signaling pathway after hypoxic-ischemic brain injury
por: Zhu, Xinzhou, et al.
Publicado: (2019)

RNA Binding Motif 5 (RBM5) in the CNS—Moving Beyond Cancer to Harness RNA Splicing to Mitigate the Consequences of Brain Injury
por: Jackson, Travis C., et al.
Publicado: (2020)

Cocaine Modulates the Neuronal Endosomal System and Extracellular Vesicles in a Sex-Dependent Manner
por: Barreto, Bryana R., et al.
Publicado: (2022)

Nutritional Supplementation Reduces Lesion Size and Neuroinflammation in a Sex-Dependent Manner in a Mouse Model of Perinatal Hypoxic-Ischemic Brain Injury
por: Brandt, Myrna J. V., et al.
Publicado: (2021)

Androstadienone modulates human aggression in a sex-dependent manner
por: Wu, Yin, et al.
Publicado: (2023)

TLR4 in POMC neurons regulates thermogenesis in a sex-dependent manner
por: Li, Yongxiang, et al.
Publicado: (2023)

Hypoxia-Ischemia-Mediated Effects on Neurodevelopmentally-Regulated Cold-Shock Proteins in Neonatal Mice Under Strict Temperature Control
por: Jackson, Travis C., et al.
Publicado: (2022)

Neurons and glial cells acquire a senescent signature after repeated mild traumatic brain injury in a sex-dependent manner
por: Schwab, Nicole, et al.
Publicado: (2022)

RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression
por: Tarn, Woan-Yuh, et al.
Publicado: (2016)

TRPV1 neurons regulate β-cell function in a sex-dependent manner
por: Bou Karam, Joey, et al.
Publicado: (2018)

Oxytocin modulates human chemosensory decoding of sex in a dose-dependent manner
por: Chen, Kepu, et al.
Publicado: (2021)

Inflammatory Responses are Sex Specific in Chronic Hypoxic–Ischemic Encephalopathy
por: Al Mamun, Abdullah, et al.
Publicado: (2018)

Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner
por: Quiñones, Mar, et al.
Publicado: (2021)

In utero thirdhand smoke exposure modulates platelet function in a sex-dependent manner
por: Ali, Hamdy E. A., et al.
Publicado: (2021)

Sex Differences in Behavioral Outcomes Following Temperature Modulation During Induced Neonatal Hypoxic Ischemic Injury in Rats
por: Smith, Amanda L., et al.
Publicado: (2015)

Oxytocin Reverses Osteoporosis in a Sex-Dependent Manner
por: Beranger, Guillaume E., et al.
Publicado: (2015)

Hedonic sensitivity to low-dose ketamine is modulated by gonadal hormones in a sex-dependent manner
por: Saland, Samantha K., et al.
Publicado: (2016)

Multifocal Cerebral Microinfarcts Modulate Early Alzheimer’s Disease Pathology in a Sex-Dependent Manner
por: Lecordier, Sarah, et al.
Publicado: (2022)

High-fat diet and estrogen modulate the gut microbiota in a sex-dependent manner in mice
por: Hases, Linnea, et al.
Publicado: (2023)

iPSC Modeling of RBM20-Deficient DCM Identifies Upregulation of RBM20 as a Therapeutic Strategy
por: Briganti, Francesca, et al.
Publicado: (2020)

Rbm24a and Rbm24b Are Required for Normal Somitogenesis
por: Maragh, Samantha, et al.
Publicado: (2014)

Nogo-A Modulates the Synaptic Excitation of Hippocampal Neurons in a Ca(2+)-Dependent Manner
por: Metzdorf, Kristin, et al.
Publicado: (2021)

Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay
por: Sun, Yue, et al.
Publicado: (2017)

RBM-5 modulates U2AF large subunit-dependent alternative splicing in C. elegans
por: Zhou, Chuanman, et al.
Publicado: (2018)

Emodin prevents hypoxic-ischemic neuronal injury: Involvement of the activin A pathway☆
por: Guo, Hongliang, et al.
Publicado: (2013)

Early-Life Stress Modulates Gut Microbiota and Peripheral and Central Inflammation in a Sex-Dependent Manner
por: Park, Hae Jeong, et al.
Publicado: (2021)

Hypoxic Training Ameliorates Skeletal Muscle Microcirculation Vascular Function in a Sirt3-Dependent Manner
por: Ma, Chunwei, et al.
Publicado: (2022)

RBM6-RBM5 transcription-induced chimeras are differentially expressed in tumours
por: Wang, Ke, et al.
Publicado: (2007)

Microbiota alters the metabolome in an age- and sex- dependent manner in mice
por: Brown, Kirsty, et al.
Publicado: (2023)

Operation Brain Trauma Therapy: An Exploratory Study of Levetiracetam Treatment Following Mild Traumatic Brain Injury in the Micro Pig
por: Lafrenaye, Audrey, et al.
Publicado: (2021)

Sex comparisons in physiological and cognitive performance during hypoxic challenge
por: Vento, Kaila A., et al.
Publicado: (2022)

Perinatal Hypoxic-Ischemic Encephalopathy
por: Lai, Ming-Chi, et al.
Publicado: (2011)

Preterm Hypoxic–Ischemic Encephalopathy
por: Gopagondanahalli, Krishna Revanna, et al.
Publicado: (2016)

RBM15 promotes hepatocellular carcinoma progression by regulating N6-methyladenosine modification of YES1 mRNA in an IGF2BP1-dependent manner
por: Cai, Xianlei, et al.
Publicado: (2021)

Epigenetic modifier Kdm6a/Utx controls the specification of hypothalamic neuronal subtypes in a sex-dependent manner
por: Cabrera Zapata, Lucas E., et al.
Publicado: (2022)

RBM10 Modulates Apoptosis and Influences TNF-α Gene Expression
por: Wang, Ke, et al.
Publicado: (2012)

Genetic variation in dopamine availability modulates the self-reported level of action control in a sex-dependent manner
por: Schlüter, Caroline, et al.
Publicado: (2019)

Morphine-context associative memory and locomotor sensitization in mice are modulated by sex and context in a dose-dependent manner
por: Hámor, Peter U., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_csvkmri9su74c9bs50jgklub68