Novel Alzheimer’s disease genes and epistasis identified using machine learning GWAS platform

Alzheimer’s disease (AD) is a complex genetic disease, and variants identified through genome-wide association studies (GWAS) explain only part of its heritability. Epistasis has been proposed as a major contributor to this ‘missing heritability’, however, many current methods are limited to only mo...

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Detalles Bibliográficos
Autores principales: Lundberg, Mischa, Sng, Letitia M. F., Szul, Piotr, Dunne, Rob, Bayat, Arash, Burnham, Samantha C., Bauer, Denis C., Twine, Natalie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582044/
https://www.ncbi.nlm.nih.gov/pubmed/37848535
http://dx.doi.org/10.1038/s41598-023-44378-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582044/
https://www.ncbi.nlm.nih.gov/pubmed/37848535
http://dx.doi.org/10.1038/s41598-023-44378-y

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