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Novel Alzheimer’s disease genes and epistasis identified using machine learning GWAS platform
Alzheimer’s disease (AD) is a complex genetic disease, and variants identified through genome-wide association studies (GWAS) explain only part of its heritability. Epistasis has been proposed as a major contributor to this ‘missing heritability’, however, many current methods are limited to only mo...
Autores principales: | Lundberg, Mischa, Sng, Letitia M. F., Szul, Piotr, Dunne, Rob, Bayat, Arash, Burnham, Samantha C., Bauer, Denis C., Twine, Natalie A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582044/ https://www.ncbi.nlm.nih.gov/pubmed/37848535 http://dx.doi.org/10.1038/s41598-023-44378-y |
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