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From himachalenes to trans-himachalol: unveiling bioactivity through hemisynthesis and molecular docking analysis

In this study, we report the first total hemisynthesis of trans-himachalol sesquiterpene, a stereoisomer of the natural cis-himachalol isolated from Cedrus atlantica essential oils, from himachalenes mixture in five steps. Reactions conditions were optimized and structures of the obtained compounds...

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Detalles Bibliográficos
Autores principales: Faris, A., Edder, Y., Louchachha, I., Lahcen, I. Ait, Azzaoui, K., Hammouti, B., Merzouki, M., Challioui, A., Boualy, B., Karim, A., Hanbali, G., Jodeh, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582069/
https://www.ncbi.nlm.nih.gov/pubmed/37848506
http://dx.doi.org/10.1038/s41598-023-44652-z